The Greater Charitable Foundation’s support has enabled HMRI to open the clinical trial internationally to over 400 participants. The results from this will directly benefit the recovery of stroke survivors.
Supporting HMRI’s medical research to improve lives
Making life-changing recoveries possible
Fiona’s post-stroke fatigue made even simple tasks like cooking impossible.
Greater Charitable Foundation’s long term support funded HMRI’s ‘Modafinil therapy’ trial, which has dramatically improved her quality of life.
HMRI Research Impact
This trial, the first of its kind, has demonstrated that post-stroke fatigue is significantly reduced after 6 weeks of modafinil therapy.
Patients also reported a significant improvement in their quality of life through improvements in their energy, mobility and thinking. Reduced fatigue also resulted in one-quarter of our study participants seeking to return to work.
In 2015, Raise were successful in receiving funding from the Greater Charitable Foundation to deliver their Bump Program for young pregnant and parenting girls aged between 13 and 23 in Gosford and Newcastle. The young women undertook weekly mentoring sessions with an experienced mother and 9 monthly workshops.
The workshops covered topic areas including employment pathways and resumes, goal setting, healthy nutrition, positive mental health, body image, healthy relationships and more. Upon completion Bump participants graduated with a TAFE Certificate I and a clear set of goals towards further education and employment.
What, Why, How
The Greater Charitable Foundation is again supporting the work of the HMRI Stroke Research Team as they undertake a Phase 3 clinical trial of ‘modafinil therapy’ in stroke survivors to assist in alleviating post-stroke fatigue and improving post-stroke quality of life.
One in 5 Australians will experience a stroke in their lifetime and 50% of people who have suffered a stroke experience severe and debilitating fatigue. Fatigue has been shown to be a predictor of patients needing help in the activities of simple daily living, and is consequentially associated with a poor quality of life, poor mood and a reduced feeling of self-worth. Current therapies to assist patients to manage post-stroke fatigue generally involve lifestyle changes or physical activity, which have very limited evidence of success.
Modafinil is an existing drug currently used safely in conditions, such as Multiple Sclerosis and narcolepsy, to promote wakefulness by stimulating pathways in the brain to increase the release of neuro transmitters. The team have recently concluded a phase 2 clinical trial testing whether modafinil could treat post-stroke fatigue with results from this trial representing a major medical breakthrough. This funding will now support a phase 3 clinical trial testing of Modafinal in a larger number of people, in order to provide the evidence required to change clinical practice.
Find out more about our current Foundation partners and their funded programs -
Improving the education, discipline, life skills, self-esteem & employment prospects of young Aboriginal men.
Supporting medical research into stroke treatment and rehabilitation.
Supporting a McGrath Breast Care Nurse to help improve the outcomes for people diagnosed with breast cancer.
Supporting a skill development and employment pathway program for disadvantaged young people, families, men and women.
The world’s first father-focused obesity prevention program for preschool-aged children, providing fathers with the knowledge, parenting skills and motivation to improve their health and become healthy role models for their children.
Giving people diagnosed with cancer the skills & knowledge to help manage the side effects of their treatment in a way that enables them to retain their confidence through the Look Good Feel Better workshops.
Supporting the Child Life Therapy program at Gold Coast University Hospital to help counteract the fears, misconceptions and anxiety that hospital experiences can provoke for children.
Supporting an intensive workshop on ‘Children’s Grief’ for school counsellors in the Hunter Region and the distribution of ‘Grief Resource Packs’ to support bereaved children and their families.